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Ep. 297: “Live at ISSCR 2025: Advancing Regenerative Medicine with CiPSCs” Featuring Drs. Hongkui Deng and Candice Liew

The Stem Cell Podcast

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HLA Knockout and Regenerative Medicine

This chapter explores the implications of HLA knockout techniques for improving immunogenicity in engineered cells for cancer treatment. It discusses the balance between short-term functionality and long-term viability of hypo immune stem cells, as well as the economic considerations of patient access to therapies. The speakers share insights into the benefits of patient-specific cells for treating diabetes, while also addressing challenges in immunosuppression and the necessity for high-quality production processes in regenerative medicine.

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