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Ep. 77: “Computational and Translational Immunology” Featuring Dr. Caleb Lareau

The Immunology Podcast

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Analyzing the Association of HHV6 with CAR T Cell Therapies

The chapter explores the role of big data in uncovering the link between herpes virus reactivation and CAR T cell therapies, emphasizing the need for critical thinking in statistical analysis. It discusses the use of a data science tool, Seratus, to identify high levels of HHV6 in T cell cultures, suggesting a potential trigger for virus reactivation. The conversation also delves into combining clinical observations with genomic data analysis to reveal insights into viral infections and their implications in immunology research.

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