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How We Can Do Better Drug Discovery | Jack Scannell

The DeSci Podcast

CHAPTER

Increasing the Lifespan of Preaged Mice

Human health span is a readout obviously humans live too long to effectively use mortality as a primary endpoint. There's an organization at the National Institute on Aging led by Richard Miller called the ITB the Interventions Testing Program in which they run lifespan studies on drugs that are suspected geroprotectors. The major impediment is just not enough preaged mice and people don't currently value that as an endpoint even though I think it should be the most valuable set of data you can possibly get.

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