Is It a Good Idea to Use Base Editors?

We are sayeing a shift over where researches are increasingly knocking out chains using base editors. Single stranded nicks and point mutations in general, are just tolerated far better by most biological systems than double stranded braks. One of the things we look at is, if you take about the opportunity for curative technology in count of some of these indications that you're alking bout it,. The latent population is so much larger than the incident rate as there's a lot of people that have sickle cell disease who are managing it with transfusions.