Follistatin Gene Therapy: Extending Canine Life

Tristan Roberts, founder of Dog Years DAO, a decentralized autonomous organization focused on improving canine longevity. They discuss the potential of using blockchain technology to manage decentralized trials and gather data more effectively. Tristan shares his journey from cognitive neuroscience to biohacking and gene therapy, detailing his experiences with HIV gene therapy and how it led to the creation of Minicircle. The conversation covers the science behind follistatin, a protein that may extend the lifespan of dogs by reducing inflammation and preventing muscle breakdown. Tristan explains the proposed methodology for the Dog Years DAO experiment, emphasizing the importance of acquiring reliable data through a system of deposits and incentives for participants. The episode also explores the ethical challenges and potential of decentralized clinical trials in the broader context of healthcare innovation.

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Timestamps

00:00 Intro

01:31 Guest Introduction: Tristan Roberts

02:16 Tristan's Journey into Gene Therapy

04:18 Gene Therapy for HIV

06:42 Canine Longevity and Gene Therapy

13:11 The Concept of Dog Year's DAO

18:58 Challenges and Future of Decentralized Trials

30:44 Closing Thoughts

Guests Links

• Tristan Roberts website
• LinkedIn
• X

Mentioned Resources

• Dog Years DAO website
• Dog Years DAO TG group
• Research Collective Telegram Group
• Longevity Events
• https://www.infinita.city/
• https://www.vitalistbay.com/
• https://edgecity.live/
• https://www.bbc.com/news/world-us-canada-41990981
• https://www.businesswire.com/news/home/20231127326868/en/FDA-Agrees-Loyal-Data-Supports-Reasonable-Expectation-of-Effectiveness-for-Large-Dog-Lifespan-Extension

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