GPR-12 Could Be Affecting Neuronal Function

This is a real amazing Twitter force because they go from identifying the receptor through this massive screen all the way to the functional experiment. It's really remarkable that you can put this virus AAV in with RNAi and knock it down sufficiently to get an effect. Well, and overexpressing a membrane protein. Yes. What I think is also cool is that they over produce this and it makes them better. That's not something gone. Yeah,. The last part of the paper goes back to some of the stuff we talked about earlier in our discussion of how changes in firing rates in the prefrontal cortex can mediate working memory. So the idea being that if you have high coupling between these