20min chapter

The Immunology Podcast cover image

Ep. 18: “Immune Microscopy” Featuring Dr. Tri Phan

The Immunology Podcast

CHAPTER

Exploring Osteomorphs and Cell Dynamics Through Advanced Microscopy

The chapter delves into the discovery of a new cell type, the osteomorph, and its behavior observed through intravital microscopy. It explores the dynamic process of osteoclasts breaking up and forming daughter cells, the potential for other undiscovered cell morphs, and the challenges of translating in vitro knowledge to in vivo cell environments. The discussion also includes insights on the role of macrophages in tissue homeostasis, the formation of multinucleated giant cells, and the relevance of osteomorphs to diseases like rheumatoid arthritis and atherosclerosis.

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