5min chapter

The Immunology Podcast cover image

Ep. 42: “Immune Mechanisms After Stroke” Featuring Dr. Arthur Liesz

The Immunology Podcast

CHAPTER

The Effects of Stroke on Neuronal Death

Many of the things that we do in stroke I think can be directly translated, of course, to acute brain injuries and also other acute lesions to the brain. And acute inflammatory bouts, we have learned induce very similar caskets. Now you asked the question about what is actually driving neuronal death. Of course, obviously stroke being a disease of iskemia, right? The primary drive is simply a lack of oxygen and glucose. So but then after this, this is initiating a very complex cascade of secondary events. In this secondary events cascade inflammation takes really a prime position. We estimated about 20% or so of the overall at issue lesion that we see tissue injury might be kind of

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