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Dr. Luke O’Neill is a Professor and Chair of Biochemistry at Trinity College Dublin, where his research group is focused on exploring the molecular basis of inflammation. His lab endeavors to provide a better understanding of the metabolic regulation of immune cell function and the innate immune system, with the aim of developing novel therapies to treat inflammatory diseases.

The Immunology Science Round Up

A Phage Counter-Defense – An orphan antitoxin counter-defense element has been discovered in phages that can overcome a bacterial toxin-antitoxin phage defense system. (5:40)

Pathogenic Memory T Cells – Researchers uncover a pathogenic subset of CD8⁺ memory T-cells that promote tissue inflammation. (14:05)

The Role of Macrophages in Graft-Versus-Host Disease – Scientists show that IL-34 reprograms macrophages to mitigate gastrointestinal complications in GVHD. (23:41)

A New Treatment Path for Nerve Damage – Research suggests that macrophages may play a protective role in preventing neuropathy from developing. (30:19)

Image courtesy of Dr. Luke O’Neill

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The Immunology Science Round Up

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