TWiV 1213: Secrets of HepB cccDNA
This Week in Virology
00:00
Unraveling Hepatitis B: From Nucleosomes to Cancer Risks
This chapter provides an in-depth exploration of molecular mechanisms related to hepatitis B virus (HBV) infections, focusing on the role of covalently closed circular DNA (cccDNA) and nucleosome dynamics. It highlights the implications of chronic HBV infections in children and the associated risks of liver diseases, including hepatocellular carcinoma. Additionally, the discussion covers vaccination's importance and treatments available, while shedding light on recent research findings on chromatin interactions in the transcriptional behavior of HBV's X gene.
Transcript
Play full episode
