Engineering an Epigenome Editor
Raising Health
00:00
CRISPR-Off - What Can We Use It For?
The marks that you made with your CRISPR-Off system were able to kind of supersede the endogenous changes that should have occurred. It's a once-and-done therapy unlike, say, RNAi or an antibody therapy. So those and other disease-causing genes are obvious use cases. The second is for cell engineering. For these, it may be viable to turn off many genes at once. And then the fourth is in this being able to program silencing at a defined time,. This is a great tool for studying the process by which these silencing marks are initiated and then propagated. A discovery tool for understanding how epigenetics works.
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