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Clozapine & Schizophrenia with Michael Cummings, MD

Psychiatry & Psychotherapy Podcast

CHAPTER

Clozapine's Complexities: Managing OCD and Medication Interactions

This chapter explores the link between clozapine and the emergence of obsessive-compulsive disorder (OCD) symptoms, detailing how serotonin antagonism can impact treatment. It highlights the challenges faced in managing schizoaffective disorder and bipolar patients, particularly concerning medication interactions and monitoring. Additionally, the chapter presents a case study illustrating the risks of combining clozapine with fluvoxamine, emphasizing the need for careful supervision in psychiatric care.

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