How to Make It To 100 With A Sharp Brain And Good Mobility
Dhru Purohit Show
Exploring the Link Between Mental Health and Brain Functionality
This chapter explores the link between mental illness and neurodegenerative diseases, focusing on the need for effective mental health solutions. It highlights critical lifestyle factors affecting brain health, including diet and exercise, to promote better cognitive functioning.
This episode is brought to you by One Skin, Bon Charge, and Manukora Honey.
As we age, many of us worry about losing the ability to move freely or manage daily tasks—and with Alzheimer’s on the rise, cognitive decline is a growing concern too. But here’s the good news: just as we can preserve mobility well into our later years, we can also maintain a sharp, healthy mind.
Today on The Dhru Purohit Show, we’re bringing you a special compilation episode featuring Dhru’s conversations with leading experts on how to live a vibrant life into your 100s.
Dr. Dale Bredesen explains why cognitive decline is no longer a mystery—and why it’s not an inevitable part of aging. He emphasizes the importance of early prevention and shares seven foundational strategies to help protect your brain decades before symptoms appear.
Juliet and Kelly Starrett join Dhru to share their practical, no-frills approach to promoting durability and mobility as we age. They cover simple at-home mobility tests like the sit-and-rise test. Their insights show how small, consistent changes in diet and movement can lay the foundation for lasting vitality and a body that recovers well from setbacks as you grow older.
Dr. Dale Bredesen is internationally recognized as an expert in Alzheimer’s disease and is the author of several New York Times bestsellers.. He serves as the principal investigator for the Alzheimer’s Disease Research Center at UCLA and founded the Alzheimer’s Drug Development Network in 2008, which helped identify new therapeutics for the disease.
Juliet Starrett is an entrepreneur, attorney, author, podcaster, and professional whitewater paddler, winning three world championships and five national titles. Dr. Kelly Starrett consults with elite athletes and coaches. Juliet and Kelly Starrett founded The Ready State fitness podcast and blog, San Francisco CrossFit, and are co-authors of the Wall Street Journal bestseller Deskbound and the New York Times bestseller Built to Move.
In this episode, Dhru and his guests dive into:
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Cognitive decline and ways to reduce the risk of developing Alzheimer’s (1:30)
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Exposure to biotoxins that contribute to cognitive decline (5:02)
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The link between mold toxicity and Alzheimer’s disease (10:58)
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Foundational diet and lifestyle strategies for Alzheimer’s prevention (20:12)
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How the brain uses energy—and why it matters (25:37)
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Tips for improving sleep quality (33:17)
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How to manage mental stress and perceived threats (36:39)
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The importance of taking high-quality fish oil daily (41:17)
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Why the sit-and-rise test is a key indicator of longevity (43:58)
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Major milestones when declines in mobility typically begin (52:40)
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Factors that influence long-term mobility (56:03)
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Supporting mobility for everyday movement and independence (1:01:33)
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At-home tests to assess your range of motion (1:05:54)
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Final thoughts and key takeaways (1:12:20)
Also mentioned:
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