What Controls the G1–S Checkpoint: Role of p53

In this episode, we explore the different phases of the cell cycle: Interphase (G1, S, G2) and the M phase (mitosis). Next, we discuss the regulation of the cell cycle and the key checkpoints that ensure its proper progression. Finally, we touch on how dysfunction in the cell cycle can lead to diseases, particularly cancer. This material is likely to appear in the Bio/Biochem section of the MCAT.

 

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[00:00] Introduction

[02:06] Overview of the cell cycle

[02:38] Two main phases of the cell cycle

[04:11] Interphase 

[12:43] Mitotic phase

[18:20] Regulation of the cell cycle

[27:09] Relevant examples of the cell cycle and disease