The Importance of Genetic Mutations in Cancer

In CML, of course, it was the exact same mutation in every single patient. In colon cancer, and other types of common cancer breast cancer, for example, that's not what you saw. You didn't see two people with the same mutations. And then the more you looked, the worse it got because so you had patient A, patient B had different genetic mutations. So complete genetic bedlam. The whole sort of somatic mutation theory, that is one or two or three mutations per cancer, was just out the window.