The Role of the Apo-E Gene in Alzheimer's

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More approaches to stemming Alzheimer's are making their way into clinical trials. Researchers aim to deliver useful molecules to the brain through vaccines, viral vexes or blood transfusions. Scientists even trying to develop vaccines to attack both tau and amyloid beta. Other researchers are betting on gene therapy to conquer forms of Alzheimer's caused by gene mutations.

Last year, researchers announced that the Alzheimer’s drug lecanemab lowered the amount of amyloid protein plaques associated with the disease in the brains of participants in a clinical trial, and slowed their cognitive decline.

Now, researchers are looking to drug combinations, vaccines and gene therapy to tackle different stages of the disease, as they forge the next generation of treatments for the condition.

This is an audio version of our Feature: Conquering Alzheimer’s: a look at the therapies of the future

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