
Toxicology Clinical Pearls
Pharmacy to Dose: The Critical Care Podcast
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Naloxone and Respiratory Complications
This chapter examines a critical case of a 34-year-old female experiencing altered mental status due to an opioid overdose and the subsequent effects of naloxone administration. It highlights the complexities of naloxone use, particularly the rare but serious complication of naloxone-induced pulmonary edema, supported by clinical studies and risk factor assessments. Through detailed analysis and case studies, the chapter underscores the importance of careful dosing and management in emergency settings to mitigate adverse respiratory outcomes.
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