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25. Diuresis & Negative Fluid Balance

Critical Care Time

CHAPTER

Optimizing Drug Delivery with Hyper-Oncotic Albumin

Exploring the use of hyper-oncotic albumin to enhance drug delivery and perfusion pressure in critical care patients with low albumin levels, such as those with cirrhosis and renal disease, citing modest benefits in increasing urine output. The chapter discusses the variability in study findings and ongoing debate surrounding the efficacy of this approach, referencing a 2014 study on albumin for diuresis augmentation and highlighting the Society of Hospital Medicine's view on unnecessary practices.

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