Are You Gong Crazy Tod McKinnon to Start a Start Up?

Tod mc kinnon quit his job and started a start up in the middle of an economic melt down. His wife, roxane, thought it was a bad idea to start a company when he had a great job and they had a great life. But there is an important lesson of greatness: Some great opportunities won't wait for your time line. How do you know when it's time to jump in and start a company right now? What are the signals that the time is now? And conversely, how do youknow when you're rushing into starting a start up when the conditions aren't right?