Oncotarget cover image

HER3: A Vital Target in Cancer Treatment

Oncotarget

CHAPTER

Challenges in Translating Preclinical Studies on HER3 Targeted Therapies to Clinical Trials

Exploring the challenges in translating preclinical studies on HER3 targeted therapies to clinical trials, including the lack of HER3 expression screening in previous trials. Emphasizing the importance of identifying HER3 expression and gene fusions as predictive biomarkers and discussing alternative HER3 activating mechanisms and compensatory tumor cell responses.

00:00
Transcript
Play full episode

Remember Everything You Learn from Podcasts

Save insights instantly, chat with episodes, and build lasting knowledge - all powered by AI.
App store bannerPlay store banner