Joel Rurik: CAR-T Therapies to Reverse Cardiac Fibrosis
Talking Biotech with Dr. Kevin Folta
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Activated Fibre Blasts - What Are They Doing?
Fibroses are activated fibre blasts associated with the scar tissue. Theres intermingling of different cell imuli coming from multiple different places to one is bio mechanical strain or stress, so excess rests on the heart. One another source of signal is escemia and reactive species from dying cardiomicites after micardifarction. Tg bata and interlucan 11 are known, potent players in the activation of fibre blasts and other immune components. And this is what tells tea cells to take up and express the r n a for the car yes.
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