Understanding Renal Tubular Acidosis and Acid-Base Balance

This chapter explores the intricate relationship between gastrointestinal losses, bicarbonate depletion, and acidosis, particularly in critically ill patients. It emphasizes the crucial roles of the kidneys in maintaining acid-base balance and the impact of high-chloride IV fluids on bicarbonate levels. The discussion also covers the diagnostic significance of renal tubular acidosis (RTA), including urine gap measurement and the importance of thorough clinical assessments.