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How to tame a toxic yet life-saving antifungal

Nature Podcast

CHAPTER

Toxicity and Potential Solutions

This chapter explores the toxicity of the antifungal drug amphotericin, particularly its harmful effects on the kidneys. Researchers discuss their attempts to modify the drug to avoid harming human cells while still being effective against fungal cells. They also highlight the progress of a new compound called AM 2-19, which shows promise in treating fungal infections and has started clinical trials.

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