#33 - Rudy Leibel, M.D.: Finding the obesity gene and discovering leptin
The Peter Attia Drive
00:00
The Genetic Defect in Prater Willie
Leptin is very highly correlated with body fat, at any level of body fat. If you stop eating, if you restrict calories, the level of lepton will drop within what period of time? Within 12, 18 hours, it'll drop by 50%. So interesting. You might have some, at least in some of these individuals, there was some reduction in body weight, but not very significant. Through the mechanism of reducing intake? Ye, primarily, apparently, yes. Although there weren't detailed, formal studies of food intake done in those in those experiments.
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