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#370 Parkinson’s Disease for Primary Care with Dr. Albert Hung

The Curbsiders Internal Medicine Podcast

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Parkinson's - Is PIM of Anserine the Best Anti-Psychotic?

There was a benefit statistically significant and looking at clinical global impression of change, there was a shift in the curve where those on ribostigmine had a better cognitive function than those not. So I think, again, it's worth trying. But with a relatively low threshold to stop the medicine if the patient's not tolerating it. Yeah. And you mentioned the psychosis. One of the biggest challenges in terms of managing psychosis in Parkinson's is that the typical medicines that we usually use as anti-psychotics we don't want to use. The dopamine antagonists that we would use for somebody who has psychosis in another context are going to make their Parkinson's worse.

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