Insomnia - The Second Corps Discovered

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There was a fascinating discovery fom a research team in australia, and it was led by the wonderful drew dawson. They found that when normal, healthy sleepers put their hands or their forearm, and even now as subsequently, their feet, into warm water, they quickly vaso dilated. When they did the same thing with insomnia patients, they didn't vaso dilate anywhere near as well. In fact, those insomnia patients didn't seem able to regulate their body temperature by using this vaso dilation response. And so they could not release that trapped heat inside of them anywhere near aswell. So in other words, they stayed hot. The degree of impaired

Today’s episode focuses on changes within the bodies of people suffering from insomnia. Almost all forms of chronic insomnia come with a significant psychological component, namely emotional distress and anxiety. This starts a Rolodex of anxiety spinning once you turn off the lights. This leads to rumination and catastrophizing, which will thwart any hopes of a good night’s sleep.

Since psychological stress is one of the principal triggers of chronic primary insomnia, researchers went in search of the underlying biological cause. We found two culprits.

First was an overactive state of the sympathetic nervous system. Under normal circumstances, it will occasionally switch on in response to a threat, kicking off a cascade response which increases your heart rate, blood flow, and metabolic rate. However, a chronic elevated flight or flight state, as occurs in insomniacs, has damaging biological consequences. A racing heart and raised metabolic rate lead to a raised core body temperature, when exactly the opposite is necessary for good sleep.

Second was the discovery of an excessive amount of activity in the adrenal cortisol-producing system (called the HPA axis) in insomniacs. When you experience a chronic state of stress, worry, and anxiety, that adrenal stress HPA axis instigates a chain of command response, resulting in the release of the wake-promoting hormone called cortisol. In good healthy sleepers, cortisol levels normally hit their lowest levels right at the point they’re falling asleep.

In insomnia patients, cortisol levels do start falling early in the evening. But then, they spike back up right at the point of bedtime. Later in the middle of the night, we also see cortisol levels once again spike in insomnia patients. These two spikes seem to overlap with the two main flavors of insomnia: sleep-onset and sleep-maintenance.

Please note that Matt is not a medical doctor, and none of the content in this podcast should be considered medical advice in any way, shape, or form, nor prescriptive in any way.

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