3min chapter

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Individualized Hemodynamic Support for Pediatric Patients with Septic Shock by S. Ranjit, et al.

OPENPediatrics

CHAPTER

Collaborative Challenges in Pediatric Sepsis Research

This chapter explores the collaborative efforts of a diverse group of authors as they tackle the challenges of writing a manuscript on pediatric septic shock. It highlights the importance of evidence-based practices while acknowledging the complexities of differing opinions and the necessity for robust clinical trials.

00:00
Speaker 1
Thank
Speaker 3
you for highlighting both the evidence that's done and the incredible practice change that it seems like you're starting to see in India and our future evidence that we need to gather going forward in the future. I want to just kind of ask a couple of questions related to the background of this manuscript. You had a lot of authors. I'm sure there were a lot of heated discussions and interesting discussions, and I would have loved to have been a fly on the wall during some of these conversations. You know, what were sort of some of the main points that were contentious and or that maybe didn't make it to the paper that you're willing to sort of share with us all?
Speaker 2
Well, first of all, it was a great learning experience with very different perspectives. I guess it takes, the first thing to realize was that there are gaps between guidelines that many of us contributed to and then actually what is being done in your own unit. And that range goes left to right, up and down. And some of it comes with reasons and some of it comes without reasons. And maybe that's the first point to realize sort of, you know, as much as we like guidelines, we do need to work on implementing guidelines and then generating evidence to tell us actually how can we keep improving our guidelines. That sort of was one.
Speaker 3
Fantastic. Thank you. So Tritra, what else do you think? Like
Speaker 1
Lorenz said, I mean, all the authors were very experienced sepsis researchers, practitioners, and everybody's got something, a protocol that works in their unit. And when you get a bunch of experts together, it's hard to, you know, in the first few iterations to get everybody on the same page. So there were a lot of questions, but it was all very respectful and mindful that there's nothing personal in it. And it's just different ways to the end result of shock resolution. So yeah, I think one of the ways that I could convince people who are initially a little reluctant, perhaps not so enthusiastic, was to say that here we are a group of 13 sepsis researchers, and maybe between us, we have collectively some expertise. So even if there's not a whole lot of evidence, maybe we can come together and suggest ways that may help a child that they're struggling with at the bedside. Although everybody needs to understand there is no trial evidence. And this is just a suggestion, something that may work. And eventually, we need to work together to ensure that there is hard evidence before it becomes widely acceptable.

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