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Freely Filtered 028: Finerenone for diabetic kidney disease
Freely Filtered, a NephJC Podcast
The Difference Between Fenerino and Spyrolactone
Spironolactone doesn't bind to the same active site that aldosterone does. A lot of these fibrotic properties that are stimulated actually need a certain level of aldo, not primary eyebrow but an elevated aldo. The FDA is definitely on board and they've got, they're convinced as long as you're getting a consistent 30% or more reduction over time, over two years, that that's a good thing.
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