Episode 8 - In the Lab: The Bethesda Assay
Bloody Minded
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Enhancing Sensitivity: The 1995 Modifications to the Bethesda Protocol
This chapter explores the 1995 modifications to the Bethesda Protocol by Dutch scientists to increase sensitivity in detecting factor VIII inhibitors. It highlights the transition to factor VIII deficient plasma for greater accuracy, while acknowledging the trade-offs in reliability and lab variability.
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