2min chapter

How I Built This with Guy Raz cover image

Moderna and Flagship Pioneering: Noubar Afeyan

How I Built This with Guy Raz

CHAPTER

Is That Right? Or Is It Rough?

The idea was that had was, could we make medicines where you inject them in order for the body to develop the proteins right to m to combat the ailment. The premonition was that it was ridiculous ecause it had never really been shown to be valuable. We quickly found out that people had tried it in the eighties, and they had caused pretty significant immune response in cells. But it turns out it's not just the m rna an the menology. You then have to figure out which cells are going to take these up. How much do they have to take up to make therapeutic doses available in your circulation? And how do you know if the protein is actually the

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