Episode 1: Properties and laws of volatile anesthetics
Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast
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What Happens in the Alveolus?
People tend to think that increasing cardiac output will speed the rate of induction with inhaled anesthetic. But all you need to remember is what happens in the alveolus. Increasing cardiac output carries more anesthetic away from theAlveolus and therefore slows the rate of induction. Infants have incredibly high alveolar ventilation which increases the speed of onset. They also have a much lower functional residual capacity (FRC) than adults. With a low FRC, there's less of a reservoir for inhaled anesthetics to escape to so FA has to rise faster. A right manstem intubation or vq mismatch can slow your induction but it will slow it
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