Love: What we do this in neuroscience, we use apparatus called a von phrase apparatus. So different diameters of... Whiskers. And so if you get one that's a filament that is so thin, I could push it onto your finger and you won't feel anything. But you keep moving up the diameter size and eventually you'll feel it. Love: It needs to be sufficient enough to open up those sodium or calcium channels to let them in. There's certain diseases. A good example would be diabetes. Particularly type 2 diabetes because it sits in the background for so many years without you knowing it. All that glucose that's so high in your blood for so long causes destruction