11min chapter

The Proof with Simon Hill cover image

Metabolic health truths | Christos Mantzoros MD, DSc, PhD

The Proof with Simon Hill

CHAPTER

Fatty Liver Disease and Evolutionary Perspectives on Fat Accumulation

The chapter explores the progression of fatty liver disease to steatohepatitis and emphasizes the importance of diet and exercise in preventing and reversing liver damage. It delves into the origins of fat accumulation in the liver, connecting it to evolutionary history marked by scarcity and efficient calorie storage, and discusses genetic and ethnic differences in fat distribution among individuals. Additionally, the chapter delves into physiological changes during starvation, highlighting the impacts on the reproductive axis and metabolic rate.

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