The key to cardiovascular disease and avoiding cardiovascular disease or minimizing the likelihood of a cardiovascular vent or stroke is so tied into endothelial health. The cells that line all blood vessels throughout the body. When we get sheer stress when we begin to exercise, you have the release of some agonists like acetylcholine histamine bradykinin which signals the cell to produce nitric oxide. And as long as that enzyme which we call nitric oxide synthase is coupled and functional, then the endothelium can dilate the blood vessels with normal vascular function. It's what mitigates and controls inflammation oxidative stress and immune dysfunctions the key contributors to all chronic disease.

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