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July 15, 2022 This Week in Cardiology Podcast

This Week in Cardiology

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Sacubitral Valsartan vs Valsartans in Heart Failure Trials

One and five patients were not able to tolerate the sacubitual valsartan during the run in. And about a third of patients discontinued the drug during the 24 weeks of the trial. Low blood pressure, low sodium, having an icy d or c r t, having mitra egagitation, not being on an ace or arb all predicted intolerance. If you have for these characteristics, there was approximately a 50% chance of intolerance.

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