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38: Does remifentanil cause opioid-induced hyperalgesia?

Depth of Anesthesia

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Understanding Opioid-Induced Hyperalgesia with Remifentanil

This chapter explores a study on opioid-induced hyperalgesia, particularly focusing on the effects of remifentanil in patients undergoing open colorectal surgery. It compares different dosages of remifentanil and their influence on pain sensitivity and morphine consumption post-operation. The findings raise concerns about increased pain and opioid usage among patients receiving higher remifentanil doses, prompting discussions on better management strategies to mitigate these effects.

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