Phase 3 trial of leniolisib in activated PI3Kδ syndrome, dabrafenib plus trametinib in relapsed/refractory hairy cell leukemia, and TγδLGL leukemia as a more symptomatic subset of leukemia
Blood Podcast
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T-Gamma Delta LGL - A Rare Chronic Lymphoproliferative Disorder
Large granular lymphocyte leukemia, or LGL, is a rare chronic lymphoproliferative disorder. LGLL occurs at a rate of 0.2 to 0.72 cases per 1 million individuals per year. Approximately 40% of LGLL cases have somatic STAT3 and STAT5B mutations. The current study represents the largest cohort of T-gamma delta LGL compiled to date.
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