Genetics and Glucocorticoid Resistance

On this episode of The Dr. Hyman Show, I sit down with Dr. Robert Hedaya, a psychiatrist who has spent decades working at the intersection of biology, brain function, and mental health. His approach starts with a different question than most psychiatry asks: what’s interfering with the brain’s ability to regulate, adapt, and repair itself? We talk about why many mental health diagnoses describe symptoms without explaining causes—and how measuring brain function, energy, and network activity is opening the door to more precise, individualized care. Watch the full conversation on YouTube or listen wherever you get your podcasts. [YOUTUBE THUMBNAIL] We discuss: • How biological imbalances can drive anxiety, depression, and cognitive symptoms • Why many “treatment-resistant” mental health issues have overlooked root causes • How brain energy and mitochondrial function influence mood and cognition • What advanced brain mapping reveals about how your brain is actually working For far too long, mental health care has focused on managing symptoms in isolation. This discussion looks at what becomes possible when we treat the brain as part of the whole system and support its ability to heal. View Show Notes From This Episode

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