TWiV 1203: What's old is flu again
This Week in Virology
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Immune Memory and Vaccine Dynamics
This chapter explores the complexities of immune memory, particularly regarding mRNA vaccines and their effectiveness against influenza strains. It discusses the concept of immune 'imprinting' and highlights a study on longitudinal immune responses to past influenza exposures, emphasizing the differences between memory and naive B cells. Additionally, the chapter examines implications for future pandemics, particularly concerning the H2N2 strain, and the role of advanced techniques in understanding antibody development.
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