There’s a thousand genes for that! (Ep 98)
Big Biology
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The Evolution of Quantitative Genetics
In 1918, Ronald Fisher showed that continuous variation could be understood as the product of a large number of genes. The rise of genome-wide association studies has revealed that most complex traits are influenced by many genes of small effect. Nick Barton is one of the world's leading evolutionary quantitative geneticists and has been at the forefront of developing and testing new theory. We talk with Nick about how the field of quantitative genetics has bridged the gap between strictly statistical approaches and the recent avalanche of DNA sequence data.
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