Addressing Polygenic Diseases?

There are two ways you could think about addressing polygenic diseases. One is a situation where many different mutations cause the same disease. The other, i think, answer to your question is cases where multiplex editing can serve as a therapy. And in general, i think the least perturbative of thegenein technology, the more promising it is for more complicated treatments that may require multiplex editing or may require lots of different editing solutions all offered to divers patient calculation.