The Emergence of the PRMT Five Inhibitors

PEDIX was one of the first to sort of plant a flag around a program that tapped into this synthetic lethal mechanism for tumor selectivity. And now we're seeing a range of companies do that it was interesting to see Amgen and Marathi are both in this space with phase one. It looks like just poking around some of the other biology abstracts in the conference or might be some cross talk between the KRS biology and PRMT five biology. This is a methyl transfer race that controls gene expression by adding methylation markers to transcription factors and other proteins, etc.