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Sep 23, 2022 This Week in Cardiology Podcast

This Week in Cardiology

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Simplicity Hypertension 3 - The Follow-Up Study

Simplicity Hypertension 3 was a sham controlled clinical trial that nearly put the kibosh on renal de-innervation therapy as a promising approach to treatment resistant hypertension. The study found no benefit for systolic blood pressure from the invasive procedure at six months or 12 months and it dampened enthusiasm in the field. But after following patients out to three years, there were significant improvements in blood pressure whether in-office or ambulatory compared with a sham controlled procedure.

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