Using CD38 Monochrome Antibody in a High Risk Patient Population

We prefer to use a car films web containing regimen so krd with a CD 38 monochrome landy bodies what we are using at mass generals. The patient also seems to have some epidural disease source a little bit of extra mid dullery extension of their myeloma as well. So the critical piece here is give your best treatment upfront to this high risk patient population trying to get them into an MRD negative state and maintaining them in that state is critically important.