Understanding Homeostasis and Allostasis in Human Physiology

The human brain is extremely complicated, but decades of careful neuroscientific research have revealed quite a bit about how it works, including how certain genes affect particular brain behaviors. Nevertheless, this progress has not led to quite as much improvement in the treatment of brain disorders as we might expect. I talk with neuroscientist Nicole Rust about why this is and how to improve the situation, as discussed in her new book Elusive Cures.

Blog post with transcript: https://www.preposterousuniverse.com/podcast/2025/06/09/317-nicole-rust-on-why-neuroscience-hasnt-solved-brain-disorders/

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Nicole C. Rust received her Ph.D. in neuroscience from New York University. She is currently a professor of psychology at the University of Pennsylvania. She is also a contributing editor at The Transmitter and an editor at BrainFacts.org. Among her awards are the Troland Research Award from the National Academy of Sciences.

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