I think for many of us we can't go get there from here for whatever reason and I would not begin to give one because this is what forces you to be agnostic about your reasons. We don't like the idea that we're no different than an animal that seeks pleasure and avoids pain but it's weird why should we want to matter just have a good time life is short enjoy yourself.
How does the mind work? What makes us sad? What makes us laugh? Despite advances in neuroscience, the answers to these questions remain elusive. Neuroscientist Patrick House talks about these mysteries and about his book Nineteen Ways of Looking at Consciousness with EconTalk host Russ Roberts. House's insights illuminate not just what we know and don't know about our minds--he also helps us understand what it means to be human.