Dose Finding Protocol in 97 Cardiovascular Surgery Patients

Sugamadex dosing varied widely from a post-attent account of zero to a train of four ratio just less than 0.9. 84 of 97 patients required less than the recommended dose and 13% required more. Two patients turned out to have recurrent neuromuscular blockade. But interestingly, none of them required more than four milligrams per kilo.