This chapter examines the pharmacology and implications of beta-2 agonists like Albuterol in exercise treatment, addressing both their benefits and side effects. It explores the mechanisms of action for beta-2 agonists and anticholinergics in bronchodilation, as well as the decision-making process clinicians face when prescribing these medications. Additionally, the chapter touches on the risks associated with various respiratory drugs, emphasizing the importance of careful management in conditions like asthma and COPD.