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17min chapter
Episode 097: Treatment of Relapsed/Refractory CLL
The Fellow on Call: The Heme/Onc Podcast
Navigating Relapsed CLL Treatment Options
This chapter examines treatment strategies for relapsed or refractory chronic lymphocytic leukemia (CLL), focusing on fixed-duration and indefinite therapies involving key medications like obinutuzumab and venetoclax. It follows a patient case to illustrate the need for careful management and evaluation amidst complications such as tumor lysis syndrome and new anemia. The discussion further emphasizes the evolving landscape of second-line therapies, including the role of BTK inhibitors and the potential for allogeneic transplants.
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