We revisit a topic covered previously as part of our “Heme/Onc Emergencies” series: heparin-induced thrombocytopenia (HIT) in Episode 017. As part of our return, we dive deeper into the pathophysiology, principles of diagnosis, and management of HIT to help you to better understand how to approach the question of “is this HIT?” as a Hematology consultant and, more importantly, how to guide management based on your index of suspicion.

Content:

- What is the pathogenesis of HIT?

- What are risk factors for HIT?

- How do we diagnose HIT?

- What are the assays that we use to make this diagnosis and how do the assays work?

- Practical points about management of HIT/HITT

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